Mean EC 50 values (red bar) and individual replicate EC 50 values (black symbols) are reported. (D) Huh-7 cells were treated with increasing doses of T3 (black), GC-1 (red), MGL-3196 (green), VK2809A (solid blue), or VK2809 (dashed blue) for 24 hrs. CPT1A RNA levels were quantified by RT-qPCR. Representative mean RQ values at each compound ...
Dose-response data are typically graphed with the dose or dose function (eg, log 10 dose) on the x-axis and the measured effect (response) on the y-axis. Because a drug effect is a function of dose and time, such a graph depicts the dose-response relationship independent of time.
Format your data in a text file as instructed in the Help for the LoadText module. Set the DefaultOutputFolder to your preferred output location and click "Analyze images". The calculated statistics (Z' factor, V factor, and EC50) will be written to Excel-compatible files. Location
It was comparable with the EC 50 value (19.65 ± 0.28 mg mL −1) of the methanol extract from Portuguese wild C. cibarius, 14 but significantly higher than the EC 50 value (2.68 mg mL −1) of scavenging ability of the DPPH radical for the methanol extract from Nigerian wild C. cibarius. 44 Ascorbic acid and α-tocopherol are both confirmed as ...